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  "Title": "Adaptive Subgroup Selection in Group Sequential Trials",
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  "Description": "Clinical trial design for subgroup selection in\nthree-stage group sequential trial. Includes facilities for\ndesign, exploration and analysis of such trials. An\nimplementation of the initial DEFUSE-3 trial is also provided\nas a vignette.",
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    {
      "page": "ASSISTant",
      "title": "Three stage group sequential adaptive design with subgroup selection",
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        "ASSISTant"
      ]
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    {
      "page": "ASSISTDesign",
      "title": "A class to encapsulate the adaptive clinical trial design of Lai, Lavori and Liao",
      "topics": [
        "ASSISTDesign"
      ]
    },
    {
      "page": "ASSISTDesignB",
      "title": "A fixed sample design to compare against the adaptive clinical trial design of Lai, Lavori and Liao.",
      "topics": [
        "ASSISTDesignB"
      ]
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    {
      "page": "ASSISTDesignC",
      "title": "A fixed sample RCT design to compare against the adaptive clinical trial design of Lai, Lavori and Liao.",
      "topics": [
        "ASSISTDesignC"
      ]
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      "page": "colNamesForStage",
      "title": "Return a vector of column names for statistics for a given stage",
      "topics": [
        "colNamesForStage"
      ]
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        "computeMHPBoundaries"
      ]
    },
    {
      "page": "computeMHPBoundaryITT",
      "title": "Compute the three modified Haybittle-Peto boundaries and effect size",
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      ]
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      "title": "The DEFUSE3 design",
      "topics": [
        "DEFUSE3Design"
      ]
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      "title": "A data generation function using a discrete distribution for Rankin score rather than a normal distribution",
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        "generateNormalData"
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